CAS 71686-01-6 kalsium cssium alfa ketoglutate

Kalsium Alpha-Ketoglutate Alpha sidoo kale waxaa loo yaqaan 'ketoglutaric acid', caano kiimiko ah c5h6o5, mid ka mid ah labada qaybood ee dhalmada ee glutaric acid, budada cryal. Cuskkeeda waa xarun bayooloji ah oo muhiim ah. Acid α-ketoglutaric acid waxay kaqeybqaadataa wareegga ashyaa'da 'Tricarxylic acid' ee noolaha, waana metabolite dhexdhexaad ah oo ku saabsan wareegga asiidhada ee Trinoxylaric, fiitamiinnada iyo aashitada dabiiciga ah iyo dheef-shiid kiimikaad. Waxaa loo istcimaali karaa sidii cunto dheeri ah, oo ay leedahay rajo ballaaran oo codsi ah.

Shaqada Codsiga

TricarByxylic Sycle

α-ketoglutate waa mid dhexdhexaad ah oo dheef-shiid kiimikaad ah oo ku yaal wareegga aashitada tricarxylorxylic ee sheyga, oo waa furaha furaha isku xidhka dheef-shiid kiimikaad-nitrogelleellar. Waxay ku taalaa ka dib aashitada ka dib iyo ka hor intaysan filcineyl Conzony-ka ku jira wareegga. Boggan, jawaab-celinta dib-u-celinta ayaa lagu guuleysan karaa in lagu buuxiyo metabolite-ka dhexdhexaadka ah iyada oo loo marayo soosaarka α-ketoglutate by trans traminate of autoglutate, iyo sidoo kale ficilka godka glutamate-ka ee glutamase. [2]

Jiilka budada amino acid

Glotamate waxaa soo saaray glutamine synthase synthase, oo u adeegsada molecule of aTP si loo soo saaro Flutamyl Phosfootate; Dhex-dhexaadkan waxaa weeraraya ammonia, oo u dhaqma sidii dib-u-habeyn nucleophilic ah, taasoo dhalisay samaynta fosfooraska glutamine iyo inortaginig.

Kaabista cuntada

Alpha-ketoglutate waxaa loo iibiyaa iyada oo ah waxyaabaha kale ee lagu daro cunnooyinka lagu daro magaca magaca AKG ama Akg si ay u jeclaadaan jimicsiga ama jiqaadeyaasha, kuwaas oo wata in walaxdu ay hagaajinayso waxqabadka tababarka ee tababarka. Tan waxaa loo sheegaa in ay ku saleysan tahay "Daraasad muujinaysa in ammonia xad-dhaaf ah ay ku xiri karto alpha-ketoglutate oo laga saari karo si loo yareeyo dhibaatooyinka badan ee la xiriira sunta ammonia". Si kastaba ha noqotee, daraasadaha kaliya ee muujiyey Alpha-ketoglutate si ay u noqdaan yareynta sunta ammonia waxay ku jirtay bukaannada ku jira hemodialysis.

Kalluulku (Alpha Ketoglutaric asiquulus) waa mid dhexdhexaad ah oo ay soo saarto ATP ama GTP ee ku taal wareegga Kreds. 2-ketoglutaric acid acid sidoo kale waxay u adeegtaa sidii laf-dhabarka ugu weyn ee kaarboon ee loogu talagalay falcelinta wax-ka-qaadidda nitrogen. 2-ketoglutaric acid acid waa xakameyn dib loo rogi karo oo ah andosinase (IC50 = 15 mm).

Sharraxaadda Wax soo saarka

Magaca wax soo saarka: kalsium alfa ketoglutate

Cas Maya.: 71686-01-6

Qaaciddada molikalalal: c5h8cao5

Miisaanka Moleculal: 188.19

Einecs No.:275-843-2

Mdl no.:mfcd026838799

Barta dhalaalaya:> 300 ° C

Xaaladda kaydinta: -20 ° C

Daahirnimo: 98%